What if a mentally disturbed person had the unthinkable idea? Well meet Martin. Martin is nothing but a mentally disturbed lonely person who lives with his emotionally abusive mother (played by Vivien Bridson). He lives in a bleak housing project. He’s got asthma, overweight, middle aged and short British ugly man. A doctor named Dr. Sebring (who played by Bill Hutchens) suspects that Martin was sexually abused repeatedly by his father when he was a child. While his father has put in prison, the audience is then going to find out that Dr. Sebring’s suspicion about sexual abuse between father and son is confirmed. Martin has a flashback to this abuse, and the audience gets to hear when the father raped his son.
Even though a loner and having so many disadvantages and traumatic life experience, Martin has a job as a security guard. His workspace is the same dark, grim and at such foreboding underground parking complex. Martin took the night shift security guard there.
Trying to escape from his mental boredom, Martin loves to watch horror film “The Human Centipede (First Sequence) and in so many times Martin loses himself out while he watches Dr.Heiter with his great surgical skills and knowledge of the human gastrointestinal system. Uneducated in the same subject like Dr. Heiter does, Martin steps forward to the unthinkable experiment.
The movie then go showing the scenes when Martin wordlessly decides to recreate the fictional experiment he saw portrayed in The Human Centipede (First Sequence). Untrained and inexperienced in medical knowledge Martin keeps going with his idea. In replacement of medical tools, Martin assembles some kitchen gadgets, woodworking tools, and assorted household items, puts them in a suitcase, and secures a gloomy, dirty, dark abandoned warehouse to recreate the film's medical experiment. Only this time, Martin intends to create not just a three-person centipede like he saw in the movie, but Martin intends to create the "full sequence" of 12 connected people.
Most of the first hour of the film the audience will watch how Martin Lomax attacks, beats, and kidnaps his victims. Any kind of people can be Martin Lomax victims, among his victims is a man and his very pregnant wife.
After collecting his victims, Martin Lomax severs the tendons in each person's legs (graphically and on screen) to prevent them from fleeing. Martin never doubt to use a hammer to knock out their teeth one by one. To stop their suicide attempts, Martin puts his fingers in their blood-filled mouths to fish out their teeth so they will not swallow and choke on them.
Lomax even becomes more and more sexually aroused by the desperation and travails of his "human centipede." The horror of the experiment causes the pregnant women to give birth while being part of the "human centipede." Lomax ignores the cries of her baby, and allows it to die. Sexually aroused by the depravities he has inflicted, Lomax wraps barbed wire around his penis and rapes the woman who is last in the "human centipede."